Relationship between inflammation and joint destruction in early rheumatoid arthritis: a mathematical description
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چکیده
منابع مشابه
Relationship between handedness and joint involvement in rheumatoid arthritis
Rheumatoid arthritis (RA) is characterized by autoimmune chronic joint inflammation, which is worsened by mechanical stress. It is still inconclusive whether joints on the right side or the dominant side get more damaged in RA since the limited number of patients analyzed in the previous study had made it difficult to separately analyze right-handed and left-handed patients. Here, we enrolled 3...
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Rheumatoid arthritis (RA) is an inflammatory progressive disease which in the absence of appropriate treatment can lead to joint destruction and disability. Prognosis of RA may be predicted based on the presence of some clinical and laboratory evidences.New criteria for classification of RA provides opportunity for earlier treatment. Initiation of treatment particularly by combination of DMARDs...
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Background. Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic polyarticular synovial inflammation. Erosive joint destruction represents a major unsolved complication of RA. Objectives. The aim of this thesis was to obtain increased knowledge of joint destruction by using a multidisciplinary approach. Firstly, the pathophysiological background of joint destruction...
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For over four decades, evidence has accumulated indicating a role for prostaglandins (PGs) in the pathogenesis of rheumatoid arthritis (1). Nevertheless, although some patients with rheumatoid arthritis may demonstrate considerable benefit from nonsteroidal anti-inflammatory drugs (2), the striking effects observed in animal models are not usually observed in most patients. Furthermore, the mor...
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Rheumatoid arthritis is an autoimmune disease characterized by the production of two known antibodies - rheumatoid factor and anti-citrullinated peptide antibody (ACPA) - against common autoantigens that are widely expressed within and outside the joints. The interactions between genes and environment are crucial in all stages of the disease, involving namely genes from major histocompatibility...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2004
ISSN: 0003-4967
DOI: 10.1136/ard.2003.015172